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Does modern treatment of early rheumatoid arthritis reduce the need for intra-articular glucocorticoids?
Authors: Weitoft T, Oberg K
PMID: 23441860 [PubMed - in process] (Source: Scandinavian Journal of Rheumatology)MedWorm Sponsor Message: Have a look at The Arthritis Daily, the new arthritis portal powered by MedWorm, with all the latest news and research on arthritis updated daily.
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Adolescents With Joint Hypermobility At Increased Risk For Joint Pain
A prospective study by U.K. researchers found that adolescents who are double-jointed - medically termed joint hypermobility - are at greater risk for developing musculoskeletal pain as they get older, particularly in the shoulders, knees, ankles and feet. Findings published in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), indicate that children with joint hypermobility are approximately twice as likely to develop pain at these joints... (Source: Health News from Medical News Today)
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The personal and national costs of lost labour force participation due to arthritis: an economic study
Conclusions:
The costs of arthritis to the individuals and the state are considerable. The impacts on the state include loss of productivity from reduced workforce participation, lost income taxation revenue, and increased government support payments -- in addition to direct health care costs. Individuals bear the economic costs of lost income and the reduction of their savings over the long term. (Source: BMC Public Health - Latest articles)
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A Threshold Hazard Model for Estimating Serious Infection Risk Following Anti-Tumor Necrosis Factor Therapy in Rheumatoid Arthritis Patients
(Source: Journal of Biopharmaceutical Statistics)
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Hydroxychloroquine effectiveness in reducing symptoms of hand osteoarthritis (HERO): study protocol for a randomized controlled trial
DiscussionThe HERO trial is designed to examine whether hydroxychloroquine is an effective analgesic treatment for OA and whether it provides any long-term structural benefit. The ultrasound substudy will address whether baseline synovitis is a predictor of therapeutic response. This will potentially provide a new treatment for OA, which could be of particular use in the primary care setting.Trial registration: ISRCTN91859104 (Source: Trials)
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Cigarette Smoke Condensate Extracts Induce IL-1-Beta Production from Rheumatoid Arthritis Patient-Derived Synoviocytes, But Not Osteoarthritis Patient-Derived Synoviocytes, Through Aryl Hydrocarbon Receptor-Dependent NF-Kappa-B Activation and Novel NF-Kappa-B Sites
Journal of Interferon & Cytokine Research , Vol. 0, No. 0. (Source: Journal of Interferon)MedWorm Sponsor Message: Have a look at The Arthritis Daily, the new arthritis portal powered by MedWorm, with all the latest news and research on arthritis updated daily.
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Interventions for nail psoriasis.
CONCLUSIONS: Infliximab, golimumab, SRT, grenz rays, and electron beam caused significant nail improvement compared to the comparative treatment. Although the quality of trials was generally poor, this review may have some implications for clinical practice.Although powerful systemic treatments have been shown to be beneficial, they may have serious adverse effects. So they are not a realistic option for people troubled with nail psoriasis, unless the patient is prescribed these systemic treatments because of cutaneous psoriasis or psoriatic arthritis or the nail psoriasis is severe, refractory to other treatments, or has a major impact on the person's quality of life. Because of their design and timescale, RCTs generally do not pick up serious side-effects. This review reported only mild ...
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Surgical versus conservative interventions for displaced intra-articular calcaneal fractures.
CONCLUSIONS: The bulk of the evidence in this review derives from one large multi-centre but inadequately reported trial conducted over 15 years ago. This found no significant differences between surgical or conservative treatment in functional ability and health related quality of life at three years after displaced intra-articular calcaneal fracture. Though it reported a greater risk of major complications after surgery, subtalar arthrodeses for the development of subtalar arthritis was significantly greater after conservative treatment.Overall, there is insufficient high quality evidence relating to current practice to establish whether surgical or conservative treatment is better for adults with displaced intra-articular calcaneal fracture. Evidence from adequately powered randomised, ...
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Diabetes Not Found To Impact Infection Risk, Surgical Outcomes
Patients with diabetes were no more likely to suffer infection, deep vein thrombosis (a deep vein blood clot) or other complications following total knee replacement (TKR) than patients without diabetes, according to new research published online, in advance of its publication in the March 2013 Journal of Bone and Joint Surgery (JBJS). The study authors sought to determine whether or not blood sugar level (glycemic control) influenced outcome in TKR. Fifty-two percent of people with diabetes have arthritis... (Source: Health News from Medical News Today)
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EU approves Novartis drug for gout
ZURICH (Reuters) - The European Commission has approved Novartis' drug Ilaris for patients with an often painful form of inflammatory arthritis, the drugmaker said on Friday. (Source: Reuters: Health)
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ARTHRITIS PAIN RELIEF (Acetaminophen) Tablet, Film Coated, Extended Release [Publix Super Markets Inc]
Updated Date: Mar 1, 2013 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
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The severity of experimental arthritis is independent of IL-36 receptor signaling
Conclusions:
The development and severity of experimental arthritis are independent of IL-36R signaling. (Source: BioMed Central)
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Kidney disease in lupus is not always "lupus nephritis"
In lupus erythematosus, elevated serum creatinine levels and urinary abnormalities implicate a kidney disorder, which may not always be lupus nephritis as defined by the current classification of the International Society of Nephrology/Renal Pathology Society. The signs of renal dysfunction may be caused by lupusunrelated renal injury such as drug toxicity or infection or by lupus-associated mechanisms that are not part of the classification, such as minimal change nephrotic syndrome or thrombotic microangiopathy. The latter seems to complicate lupus nephritis more frequently than previously thought. An unbiased assessment of kidney disease in lupus requires a kidney (re-)biopsy to define the appropriate management. (Source: Arthritis Research and Therapy)
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EQUATE ARTHRITIS PAIN (Acetaminophen) Tablet, Film Coated, Extended Release [Wal-Mart Stores Inc]
Updated Date: Mar 1, 2013 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
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Distinguishing Lyme From Septic Knee Monoarthritis in Lyme Disease-Endemic Areas
Children with Lyme and septic arthritis of the knee may present similarly, although septic arthritis requires prompt treatment initiation to avoid joint destruction. Clinicians must make initial management decisions without Lyme serology and bacterial culture results.
Our clinical prediction rule accurately identified patients at low risk for septic arthritis in a Lyme disease–endemic area. In the appropriate clinical context, low-risk patients may be spared invasive testing such as diagnostic arthrocentesis. (Read the full article) (Source: PEDIATRICS)MedWorm Sponsor Message: Have a look at The Arthritis Daily, the new arthritis portal powered by MedWorm, with all the latest news and research on arthritis updated daily.
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ARTHRITIS PAIN RELIEF TEMPORARY MINOR (Acetaminophen) Tablet, Film Coated, Extended Release [Kroger Company]
Updated Date: Mar 1, 2013 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))MedWorm Sponsor Message: Have a look at The Arthritis Daily, the new arthritis portal powered by MedWorm, with all the latest news and research on arthritis updated daily.
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MAPAP ARTHRITIS PAIN (Acetaminophen) Tablet, Film Coated, Extended Release [Major Pharmaceuticals]
Updated Date: Mar 1, 2013 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
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ARTHRITIS HP (Apis Mellifica, Bryonia, Causticum, Colchicum Autumnale, Kalmia Latifolia, Ledum Palustre) Liquid [BioActive Nutritional, Inc.]
Updated Date: Mar 1, 2013 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
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ACETAMINOPHEN ARTHRITIS PAIN (Acetaminophen) Tablet, Film Coated, Extended Release [Western Family Foods Inc]
Updated Date: Mar 1, 2013 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
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CARE ONE ARTHRITIS PAIN RELIEF TEMPORARY MINOR (Acetaminophen) Tablet, Film Coated, Extended Release [American Sales Company]
Updated Date: Mar 1, 2013 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
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